Yes, but check your device first.
Wyze Headphones can connect to most Bluetooth-capable devices. But be sure to check your device's compatibility as some consoles (Xbox One, Nintendo Switch, and PS4, to name a few) restrict all direct Bluetooth connection from third-party devices.
Are you using Wyze Headphones with a 3.5 mm AUX cable? The included 3.5 mm "TRS" (tip-ring-sleeve) cable does not have a built-in microphone. If you're using Wyze Headphones with a wired connection to your computer or gaming console, you must purchase a third-party "TRRS" (tip-ring-ring-sleeve) cable with a built-in microphone.