No, but setup in the app is recommended.
You can use Wyze Gun Safe without the Wyze app, and without connecting to it via Bluetooth. Simply use the included keys to access the safe.
However, we recommend setting up the safe in the Wyze app. In the event that you lose your Backup Keys, or accidentally lock the keys inside the safe, you will lose access to the safe and won't have an alternate entry method if it's not set up in the app.
You can set up the safe in the app, set an access code and save your fingerprint, then delete the app if you'd like. You can still access the safe with those methods even without the app as long as you've set it up first.
Related articles: Never put your Backup Keys inside Wyze Gun Safe, How do I open Wyze Gun Safe?