Yes, but it will only measure your weight.
If you step on the scale with socks and/or shoes on, your Wyze Scale device will only be able to measure your weight. To take your other body composition measurements (ex. Body Fat %, Water %) you must step on the scale with both feet while barefoot.
This applies to all Wyze Scale devices: Wyze Scale Ultra BodyScan, Wyze Scale Ultra, Wyze Scale X, Wyze Scale S, and Wyze Scale.