Nope! Wyze Bulbs are UL certified which includes a safety test for temperature. That said, Wyze Bulbs will get warm during operation (though they're much cooler than Incandescent bulbs) so we recommend turning your Wyze Bulb off and giving it a few minutes to cool down before handling.
If you absolutely need to touch the bulb while it's on, make sure to grab the top plastic part (where the light comes out) instead of the metal heat sink.
Additionally, avoid using your Wyze Bulb in a fully enclosed light fixture which may cause your Wyze Bulb to overheat and thereby reduce its life expectancy.